The PQI Podcast

S9 E4: Advancing Pharmacogenomics in Oncology

Episode Notes

How can genetic insights change the way we treat cancer?

In this episode of the PQI Podcast, Dr. Soni Tuteja, Director of Pharmacogenomics at Penn Medicine, shares how her team put pharmacogenomic testing into practice — and the impact it’s had on patients. She highlights findings from her Journal of Clinical Oncology article on DPYD and UGT1A1 testing in GI cancers, showing how pre-treatment testing helped reduce toxicities, guide dose adjustments, and support safer therapy.

Listeners will also hear about:

• Practical strategies to expand and sustain pharmacogenetic testing in real-world settings
• How pharmacists can lead patient counseling and program implementation
• The role of NCODA’s Positive Quality Interventions (PQIs), like DPYD testing before fluoropyrimidine treatment, in helping teams deliver safer, more personalized care